Children's Gripe Mixture or Gripe Mixture or Infant Sugar Free Gripe Mixture or Children's 1 Month Plus Gripe Mixture or Boots Gripe Mixture 1 Month Plus
| Active ingredient|| % Quantity|
| Sodium Bicarbonate EP|| 1.0 w/v|
For the relief of wind and griping pains.
For oral administration.
Babies up to 1 month: Not Recommended.
Infants 1 - 6 months: 5ml.
Infants 6 months - 1 Year: 10ml.
The above doses may be repeated before or after each feed up to six times in 24 hours if needed.
Not recommended for children over 1 year.
Hypersensitivity to sodium bicarbonate, or any of the ingredients.
Metabolic or respiratory alkalosis
Patients on low sodium diets
Congestive heart failure
Impaired renal function
Cirrhosis of the liver
Babies under one month of age or over one year of age.
Do not exceed the recommended dose as excess use may lead to alkalosis.
This medicine should be given to the child to swallow before or after feeds. Inclusion of this medicine in feeds or bottles has not been studied and should be avoided.
Keep all medicines out of the reach of children.
The effect of oral bicarbonate compounds in raising intra-gastric pH may reduce or increase the rate and/or extent of absorption of a number of medicines. Alkalinisation of the urine leads to increased renal clearance of acidic drugs such as salicylates, tetracyclines and barbiturates. Conversely, it prolongs the half life of basic drugs.
Sodium bicarbonate enhances lithium excretion.
The safety of sodium bicarbonate during pregnancy and lactation has not been established but its use during these periods is not considered to constitute a hazard.
Immune system disorders: Rarely hypersensitivity reactions including skin rash
Gastrointestinal disorders: Stomach cramps, belching, flatulence, vomiting
General disorders and administration site conditions: Malaise
Metabolism and nutrition disorders: Excessive use may lead to hypernatraemia and hyperosmolality, hypokalaemia and metabolic acidosis, especially in patients with impaired renal function
Reporting of suspected adverse reactions
Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product. Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard
Overdosage with this medicine may give rise to the symptoms of hypernatraemia, which may include drowsiness and irritability, pyrexia, tachypnoea and hyperpnoea. In more severe instances of acute sodium overload signs of dehydration and convulsions may occur.
Treatment of hypernatraemia includes repair of any dehydration present and the gradual reduction of plasma sodium. The alkalosis, if present, will respond usually to the treatment of hypernatraemia. At all times, intensive monitoring of electrolytes and patient's circulation and central nervous system is essential.
Sodium Bicarbonate has antacid properties.
Sodium bicarbonate causes neutralisation of gastric acid with the production of carbon dioxide. Any bicarbonate not involved in that reaction is absorbed and in the absence of a deficit of bicarbonate in the plasma, bicarbonate ions are excreted in the urine that is rendered alkaline and there is an accompanying diuresis.
Apple flavour 5112O1E
24 months unopened
12 weeks after opening
A clear polythene terephthalate bottle with a polypropylene child resistant closure fitted with an expanded polyethylene liner.
Pack size: 150ml
The Boots Company Plc
1 Thane Road West
Nottingham NG2 3AA
| Date of First Authorisation:|| 24 October 1990|
| Date of Last Renewal:|| 20 February 1996|